مطالعه مسمومیت های ناشی از اقدام به خودکشی در منطقه غرب استان مازندران در سالهای 1376-1373

Background and purpose : Acute poisoning due to suicide , is one of the most important factors providing social and problems in developing countries. This study was designed to determine the prevalence of attempted suicide by poisoning in the west of Mazandaran. Patients and Methods : A total of 301 intentional Poisoning cases referred to hospitals located the west of Mazandaran (Tonekabom and Pamsar) during 1994-1997 , were included in this study. Various parameters in relation to poisoning and patients been investigated retrospectively in these cases. Results : In this study , 97.1% of patients were outpatient and others were hospitalized. Data in these cases showed greater rate of poisoning in males(53%) than famales(47%) , but the mortality rate was higher in females (15 versus 2 cases). Most poisoning victims were at the age range of 16-25 years. Oral ingestion was the only route of intoxication. Most cases of intentional poisoning were referred to hospitals at the sfternoon. Attempt to suicide with drugs was more than pesticides (41.5% versus 31.5%) , and other agents such as chemicals (15.9%) , opium (7%) and unknown causes (4.1%). Among the drugs , benzodiazepine (18%) was the first, followed by cardiovascular agents (9%), antiepileptics (6%)antidepressants (5%) and neuroleptics (3%). In 49.3% of cases, specific antidotes were used. Finally, about 90% of the patients recovered without any sequelae, 3.3% were referred to other centers and 5.6% died. Conclusion : More careful consideration should be given to limit to limit and control the availability of drugs and chemicals (such as organophosphate pesticides). Attention should ne paid to special groups such as females and adolescents. Further attempts to establish poison information and control centers in different parts of this province is highly suggested